#1. The Department of Justice
Gambling affiliates are subject to the regulatory whims of big government and no arm of government wields it power more erratically than the US Department of Justice.
One day the DOJ is content to turn a blind eye to online poker, and the next day they shut down the entire US market. Flash forward a year and they’ve decided that maybe poker isn’t so bad after all.
You just never know where the DOJ is going to strike next and that makes them the #1 threat to gambling affiliates.